[@RenaissancePeriodization] The Most Dangerous Supplements People Still Take

Link: https://youtu.be/NkdtQn6mtbA

Short Summary

This video discusses several dangerous supplements and drugs, including Carterine (GW501516), DNP, Oxy Elite Pro, lipocinetics, DMAA, Superdrol, Methyltrenbolone, and Rimonabant (Accomplia), highlighting their severe side effects ranging from cancer and organ failure to psychiatric disorders and death. The speaker advises viewers to research thoroughly and exercise caution before using any new or hyped supplements, emphasizing that "natural" does not equate to safe.

Key Quotes

Here are four direct quotes that capture valuable insights from the video:

1. "When we're talking transplants, this stuff is as liver toxic as it gets." (Referring to the hepatotoxicity of a supplement where liver failure required transplants)
2. "As a person who is trying to give you guys the real deal on how the real CD drug world actually works, I'm not going to tell you nobody uses DMP. That is a fucking lie. I will not lie to you today in the last 30 seconds. I have a huge dick." (Illustrating the speaker's commitment to honesty, though humorously)
3. "Almost everyone I ever talked to says two things about it. One, it's amazing. And two, you legit feel like you're going to have a heart attack." (Describing user experience with DMAA, highlighting the danger despite the perceived benefits.)
4. "What it tells us isn't that drugs are bad. It doesn't even tell us that artificial things are bad because one of the worst ones here was a natural substance. What it tells us is before you go putting stuff into your bodies that you see advertised or some pro is taking it or you saw it in some peptide shop, do your due diligence." (The speaker's summary of the video's main point: do your research!)

Detailed Summary

Here's a detailed summary of the YouTube video transcript, broken down into bullet points:

Key Topics:

• Discussion of extremely dangerous supplements and drugs historically marketed for fat loss, endurance, and performance enhancement.
• Highlighting the significant risks associated with these substances, including cancer, organ failure, heart attack, stroke, and death.
• Emphasizing the importance of research and caution before using any new or unproven supplement or drug.
• Providing real-world perspective on drug use in hardcore communities, including motivations and dose considerations.
• Promoting the RP Diet Coach app as a safe and effective alternative for achieving fitness goals.

Specific Drugs and Supplements Discussed:

• Cardarine (GW501516/Endurabal):

  • Marketed for fat loss and endurance.
  • Demonstrated tumor formation in rats and mice during carcinogenicity trials.
  • Largely abandoned by even hardcore drug users due to cancer risks.
  • Still available for purchase online despite known dangers.

• 2,4-Dinitrophenol (DNP):

  • Industrial chemical and explosive; not approved for human use.
  • Mitochondrial uncoupler, leads to rapid fat loss by increasing heat production and calorie expenditure.
  • Extremely dangerous; high doses can lead to fatal overheating and delirium.
  • Dosage matters: While extremely dangerous at high doses (1000mg+), some use it at low doses (50-100mg).
  • Quality control of DNP can be a problem as it is purchased from agricultural suppliers.
  • Side effects include feeling hot and weak.
  • Considered less beneficial than other fat loss methods.

• Oxy Elite Pro (Ageline formula):

  • Marketed as a thermogenic fat loss supplement.
  • Caused a severe outbreak of hepatitis and liver failure.
  • Resulted in hospitalizations and liver transplants.
  • Pulled from the market due to its dangerous effects.
  • Showcases the risk of new "super" supplements.

• LipoKinetics (Enic acid):

  • Marketed as a natural product.
  • Has uncoupling properties (similar to DNP) at high doses.
  • Severely hepatotoxic; caused fulminant liver failure and required transplants.
  • Emphasizes that "natural" does not equal safe.

• DMAA (1,3-dimethylamylamine/methylhexanamine):

  • Super stimulant used in pre-workouts like Jack3D.
  • Produced significant boosts in focus, aggression, and performance.
  • Caused high blood pressure, vasoconstriction, heart attacks, and strokes.
  • FDA ruled it illegal in dietary supplements.
  • Users loved the effects but acknowledged the risk of heart attack.

• Methasterone (Superdrol):

  • A very strong oral steroid sold as a supplement in the 2000s.
  • Causes radical strength and muscle mass gains.
  • Causes severe cholestatic liver injury.
  • Considered more dangerous than other steroids by most users.

• Methyltrienolone (Methyltren):

  • Extremely anabolic and androgenic at tiny doses.
  • Extremely liver toxic and has severe psychological effects.
  • Used acutely by some powerlifters on competition day for strength boost.
  • Generally avoided for regular use.

• Rimonabant (Accomplia):

  • CB1 receptor antagonist marketed for weight loss.
  • Withdrawn medication in the EU due to severe adverse psychiatric effects (depression, anxiety, suicidal ideation).
  • Highlights the importance of considering mental health risks when taking weight loss medications.

Arguments and Information:

• The dangers of blindly trusting marketing claims and hype surrounding new supplements.
• The importance of researching ingredients and potential side effects.
• That even "hardcore" drug users avoid certain substances due to unacceptable risks.
• The variability in individual responses to drugs and supplements.
• The potential for product contamination and inaccurate dosage information.
• That the effectiveness of a drug does not negate its dangers.
• The importance of understanding that "natural" does not automatically mean safe.
• The consideration of risk vs reward when considering these types of drugs/supplements.
• The suggestion to seek information from a variety of sources regarding the safety and effectiveness of certain substances before taking them.
• The use of the RP Diet Coach app as a safe alternative for achieving fitness goals.